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Cronobacter sakazakii 대표 이미지

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출처: English Wikipedia - Species Pages
Cronobacter is the officially recognised bacterial genus name for the organism which before 2007 was named Enterobacter sakazakii. The name Enterobacter should no longer be used as the genus name as Cronobacter has been accepted in the International Journal of Systematic and Evolutionary Microbiology, along with the description of the new species.[2][3] . It is a Gram-negative, rod-shaped, pathogenic bacterium. The majority of Cronobacter cases are in adults, and additionally it is associated with a rare cause of invasive infection of infants with historically high case fatality rates (40–80%).[4][5][6] In infants it can cause bacteraemia, meningitis and necrotising enterocolitis. Some neonatal C. sakazakii infections have been associated with the use of powdered infant formula[4][6] with some strains able to survive in a desiccated state for more than two years.[7] However not all cases have been linked to contaminated infant formula. In November 2011, several shipments of Kotex tampons were recalled due to a Cronobacter (E. sakazakii) contamination.[8] All Cronobacter species, except C. condimenti, have been linked retrospectively to clinical cases of infection in either adults or infants.. However multilocus sequence typing [9] has shown that the majority of neonatal meningitis cases in the past 30 years, across 6 countries have been associated with only one genetic lineage of the species Cronobacter sakazakii called 'Sequence Type 4' or 'ST4',[10] and therefore this clone appears to be of greatest concern with infant infections. The bacterium is ubiquitous being isolated from a range of environments and foods, and the majority of Cronobacter cases are in the adult population. However it is the association with intrinsically or extrinsically contaminated powdered formula which has attracted the main attention.According to multilocus sequence analysis (MLSA) the genus originated ~40 MYA, and the most clinically significant species, C. sakazakii, was distinguishable ~15-23 MYA. .[11] E. sakazakii was defined as a species in 1980 by Farmer et al.. DNA-DNA hybridization showed that E. sakazakii was 53–54% related to species in two different genera, Enterobacter and Citrobacter. However, diverse biogroups within E. sakazakii were described and Farmer et al. suggested these may represent different species and required further research for clarification.[1] The taxonomic relationship between E. sakazakii strains has been studied using full-length 16S rRNA gene sequencing, DNA-DNA hybridization, multilocus sequence typing (MLST), f-AFLP, automated ribotyping. This resulted in the classification of E. sakazakii as a new genus, Cronobacter within the Enterobacteriaceae, initially comprising four named species in 2007. The taxonomy was expanded to five named species in 2008, and more recently (2011) to seven named species.[2][3][12] The initial four named species in 2007 were Cronobacter sakazakii (comprising two subspecies), C. turicensis, C. muytjensii and C. dublinensis (comprising three subspecies) plus an unnamed species referred to as Cronobacter genomospecies I. The taxonomy was revised in 2008 to include a fifth named species C. malonaticus, which in 2007 had been regarded as a subspecies of C. sakazakii. In 2012, Cronobacter genomospecies I was formally renamed Cronobacter universalis, and a seventh species was described called Cronobacter condimenti.
국문 설명
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국가생명연구자원통합정보시스템 연계 데이터 (전체 데이터 건수: 6637)
번호 ID 자원고유번호 학명 대구분 중구분 연계기관 연계정보조회
1 8153651 BI3699814 Cronobacter sakazakii 기타 단백질서열정보 서울대학교 조회
2 8166480 BI3712678 Cronobacter sakazakii 기타 단백질서열정보 서울대학교 조회
3 8166481 BI3712679 Cronobacter sakazakii 기타 단백질서열정보 서울대학교 조회
4 8166482 BI3712680 Cronobacter sakazakii 기타 단백질서열정보 서울대학교 조회
5 8166483 BI3712681 Cronobacter sakazakii 기타 단백질서열정보 서울대학교 조회
6 8166484 BI3712682 Cronobacter sakazakii 기타 단백질서열정보 서울대학교 조회
7 8166485 BI3712683 Cronobacter sakazakii 기타 단백질서열정보 서울대학교 조회
8 8166486 BI3712684 Cronobacter sakazakii 기타 단백질서열정보 서울대학교 조회
9 8166487 BI3712685 Cronobacter sakazakii 기타 단백질서열정보 서울대학교 조회
10 8166488 BI3712686 Cronobacter sakazakii 기타 단백질서열정보 서울대학교 조회
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